The doctor's spirit infects Sam with extreme rage, causing him to turn against Dean and even shoot him with rock salt.
The episode centers on a developer making a horror game based on the "Murder House" from Season 1 of the original series. [S1E7] Asylum
Dick, Kory, Gar, and Rachel head to the asylum knowing it's likely a trap but wanting to save Rachel's mother, Angela. The doctor's spirit infects Sam with extreme rage,