Supplemental information, including data sets and molecular models, is also available for download on the same page. Synapses: Changing the size of dendritic spines - eLife
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Download links * Insight. * Structural Biology and Molecular Biophysics. * CaMKII. * actinin. * long-term potentiation. * synapse.
Understanding how dendritic spines change size helps researchers decipher the brain's "wiring" and how it stores information. Disruptions in this structural plasticity are often linked to various neurological and cognitive disorders.
The study investigates the role of specific proteins, including CaMKII (Calmodulin-dependent protein kinase II) and actinin , in managing the structural integrity and growth of the dendritic spine.