109595 Page

: A review from MIT researchers (indexed under 109595 ) examines manganese-based oxides as catalysts for energy conversion in fuel cells.

: While this "primed" state might seem helpful for fighting infections, it often leads to pathological inflammation , increasing the risk for cardiovascular diseases, autoimmune disorders, and severe inflammatory responses (such as those seen in COVID-19). Critical Review and Assessment

: The study is lauded for its translational approach , showing consistent results across both animal models and human subjects, which adds high clinical relevance. 109595

: In both mice and humans, chronic stress was found to reprogram myeloid progenitor cells in the bone marrow. This leads to an increased production of monocytes that are more reactive to future threats.

The methodology and findings of this study have been widely cited in the medical community for bridging the gap between psychology and physical pathology. : A review from MIT researchers (indexed under

: It also refers to a recent eLife reviewed preprint (109595) that uses fruit flies to model RVCL-S , a rare genetic disease affecting blood vessels in the brain and retina.

: The study identifies specific epigenetic changes—molecular "marks" on DNA—that alter how immune cells respond to inflammation even after the stressor is removed. : In both mice and humans, chronic stress

: Experts note that while the "priming" is clearly observed, the exact duration of these epigenetic changes remains an open question for future research.